From 3-6 May 2025, Nutritional Therapy for IBD joined the global digestive health community at Digestive Disease Week® in San Diego, CA.
Here are some key highlights on nutrition, IBD, and the gut microbiota:
✅ While what we know about the microbiome comes from studying feces (large intestine), the small intestine microbiome is different and may play a role in:
🔸Abdominal pain
🔸IBS with diarrhea
🔸The recovery after antibiotics
✅ A flexible diet may have a space in the management of IBD alongside the standard of care:
🔸The plant-based nature of a diet seems to be more relevant than cutting out calories to relieve symptoms of depression.
🔸A plant-based calorie-restricted diet may improve symptoms and decrease C-reactive protein in mild-to-moderate Crohn’s disease.
🔸A catered low-fat, high-fiber diet may improve Crohn’s disease symptoms, inflammation, and quality of life.
🔸Time-restricted feeding may improve metabolic health in patients with Crohn’s disease and overweight.
✅ Healthy diets with adequate dietary fiber (more than 25 g/day) are well tolerated in quiescent IBD.
✅ Restrictive eating in gastrointestinal conditions could be a maladaptive coping strategy* in some patients.
*Strategy related to emotional states, fatigue/boredom, and external factors that feel good temporarily but often aren’t helpful long-term or make it worse.
✅ Gut bugs are becoming central players in IBD 👉 new potential treatments could hijack tryptophan metabolism towards anti-inflammatory metabolites.
✅ Moving from a high to low area with poor presence of IBD 👉 allows the adoption of the host country lifestyle 👉 normalization of the high risk of IBD over one to two generations.
✅ The lack of gut microbes involved in the metabolism of food 👉may contribute to explaining why adverse reactions to foods are common in IBD (more than one food components are involved!)
👉 Stay tuned for extensive nutritional highlights and key takeaways from DDW 2025 in the June newsletter!